Alan L Rothman Selected Research

Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

10/2009	Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.
5/2009	TNF and LTA gene, allele, and extended HLA haplotype associations with severe dengue virus infection in ethnic Thais.
6/2005	Proinflammatory factors present in sera from patients with acute dengue infection induce activation and apoptosis of human microvascular endothelial cells: possible role of TNF-alpha in endothelial cell damage in dengue.
11/2003	Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells.
6/2002	Dengue-specific T cell responses in peripheral blood mononuclear cells obtained prior to secondary dengue virus infections in Thai schoolchildren.
6/2002	Increased production of interleukin-8 in primary human monocytes and in human epithelial and endothelial cell lines after dengue virus challenge.
5/2002	Cytokine gene expression and protein production in peripheral blood mononuclear cells of children with acute dengue virus infections.

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Alan L Rothman Research Topics

Disease

57	Infections 01/2021 - 05/2002
42	Dengue (Dengue Fever) 01/2021 - 05/2002
11	Severe Dengue 01/2017 - 05/2002
9	Coinfection 01/2019 - 04/2007
8	Virus Diseases (Viral Diseases) 03/2014 - 05/2002
3	Yellow Fever 02/2011 - 09/2009
3	Viremia 10/2008 - 05/2002
3	Vaccinia 10/2004 - 04/2002
2	Asymptomatic Infections 01/2019 - 12/2018
2	Convalescence 10/2016 - 01/2011
2	Human Influenza (Influenza) 08/2015 - 07/2013
2	Hepatitis C 01/2011 - 04/2006
2	Fibrosis (Cirrhosis) 01/2011 - 04/2006
2	Thrombocytopenia (Thrombopenia) 05/2006 - 05/2002
2	Smallpox (Variola) 04/2003 - 06/2002
1	Inflammation (Inflammations) 01/2021
1	Shock 08/2016
1	Fever (Fevers) 12/2013
1	Japanese Encephalitis 07/2010
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 10/2009
1	Acute Disease 08/2009
1	Genetic Predisposition to Disease (Genetic Predisposition) 10/2008
1	Reinfection 09/2008
1	Hypersensitivity (Allergy) 08/2008
1	Injection Site Reaction 08/2008
1	Vasculitis (Vasculitides) 08/2008
1	Necrosis 07/2008
1	Melanoma (Melanoma, Malignant) 07/2008
1	Leptospirosis 12/2007

Drug/Important Bio-Agent (IBA)

21	VaccinesIBA 01/2021 - 04/2002
17	CytokinesIBA 01/2019 - 05/2002
15	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2002
11	EpitopesIBA 04/2020 - 06/2002
10	Neutralizing AntibodiesIBA 05/2016 - 03/2004
9	AntibodiesIBA 01/2021 - 03/2004
7	Dengue VaccinesIBA 01/2021 - 07/2011
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009 - 05/2002
6	RNA (Ribonucleic Acid)IBA 01/2021 - 04/2006
6	Peptides (Polypeptides)IBA 01/2021 - 06/2002
5	Immunoglobulin M (IgM)IBA 01/2021 - 12/2007
5	AntigensIBA 10/2016 - 06/2002
5	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2014 - 06/2002
5	Antiviral Agents (Antivirals)IBA 01/2011 - 04/2006
4	InterferonsIBA 04/2006 - 06/2002
3	Interferon-gamma (Interferon, gamma)IBA 04/2009 - 05/2002
3	Interleukin-8 (Interleukin 8)IBA 04/2006 - 06/2002
3	EnzymesIBA 10/2004 - 06/2002
2	Immunoglobulin G (IgG)IBA 01/2021 - 04/2020
2	IgG Receptors (Fc gamma RI)IBA 01/2021 - 08/2005
2	Immunoglobulin A (IgA)IBA 01/2021 - 04/2020
2	Interleukin-2 (IL2)IBA 01/2019 - 10/2009
2	Chemokine CCL5IBA 12/2018 - 09/2005
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2018 - 12/2007
2	HLA-A Antigens (HLA-A)IBA 01/2011 - 03/2006
2	ChemokinesIBA 10/2008 - 09/2005
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2008 - 06/2005
2	Transaminases (Aminotransferases)IBA 02/2008 - 05/2002
2	NF-kappa B (NF-kB)IBA 04/2006 - 09/2005
2	InterleukinsIBA 04/2006 - 05/2002
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2021
1	micaIBA 01/2020
1	Indicators and Reagents (Reagents)IBA 12/2018
1	Interleukin-15 (Interleukin 15)IBA 12/2018
1	Interleukin-6 (Interleukin 6)IBA 12/2018
1	Interleukin-12 (IL 12)IBA 12/2018
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2018
1	Serine (L-Serine)FDA Link 01/2017
1	Dynamins (Dynamin)IBA 01/2017
1	Immunoglobulin D (IgD)IBA 10/2016
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 08/2016
1	HLA-B44 AntigenIBA 09/2015
1	ProteomeIBA 09/2015
1	Viral RNAIBA 01/2012
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2011
1	Yellow Fever Vaccine (Vaccine, Yellow Fever)FDA Link 07/2010
1	ChimeriVaxIBA 07/2010
1	Interleukin Receptor Common gamma SubunitIBA 10/2009
1	HLA-A2 Antigen (HLA A2 Antigen)IBA 10/2009
1	Lymphotoxin-alpha (Lymphotoxin)IBA 05/2009
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 04/2009
1	Messenger RNA (mRNA)IBA 04/2009
1	DNA (Deoxyribonucleic Acid)IBA 08/2008
1	Interferon Type IIBA 07/2008
1	Histocompatibility Antigens Class IIBA 07/2008
1	Galectin 3 (LGALS3)IBA 07/2008
1	Carrier Proteins (Binding Protein)IBA 07/2008
1	Factor VII (Proconvertin)IBA 07/2008
1	LigandsIBA 07/2008
1	Serum AlbuminIBA 12/2007
1	Immunoglobulins (Immunoglobulin)IBA 04/2007
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2007
1	Cell Adhesion MoleculesIBA 09/2006
1	Interleukin-11 (Interleukin 11)IBA 05/2006
1	Thrombopoietin (c-mpl Ligand)IBA 05/2006
1	Biomarkers (Surrogate Marker)IBA 05/2006
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 04/2006
1	LuciferasesIBA 04/2006

Therapy/Procedure

1	Tourniquets 10/2018
1	Resuscitation 08/2016
1	Therapeutics 04/2006